Health-related quality of life and long-term prognosis in chronic hypercapnic respiratory failure: a prospective survival analysis

Table 2 Results of SRI questionnaire within subgroups.

SRI – subscore	All (n = 231)	COPD (n = 98)	RD (n = 49)	NMD (n = 15)	OHS/OL (n = 69)
Respiratory complaints	61.2 ± 19.8	50.9 ± 17.5	65.8 ± 17.7***	59.4 ± 13.9*	72.3 ± 18.7***
Physical functioning	49.4 ± 24.9	38.2 ± 21.6	55.0 ± 24.7**	33.6 ± 18.0	64.2 ± 22.0***
Attendant symptoms/sleep	63.6 ± 19.0	58.9 ± 18.2	65.8 ± 19.4	59.0 ± 16.5	69.4 ± 19.1***
Social relationship	71.9 ± 18.5	64.9 ± 19.9	75.8 ± 14.6**	68.8 ± 14.3	79.3 ± 16.5***
Anxiety	62.5 ± 23.6	51.8 ± 21.6	66.9 ± 24.2**	61.7 ± 19.1	74.1 ± 20.7***
Psychological wellbeing	62.9 ± 19.6	55.7 ± 19.2	68.3 ± 19.0**	53.6 ± 12.7	70.9 ± 17.4***
Social functioning	58.2 ± 23.3	47.3 ± 20.9	66.2 ± 23.7***	50.3 ± 16.6	68.8 ± 21.5***
Summary score	61.2 ± 17.7	52.2 ± 15.6	66.2 ± 17.2***	55.3 ± 9.2	71.3 ± 15.7***

Definition of abbreviations: SRI = Severe Respiratory Insufficiency Questionnaire; COPD = chronic obstructive pulmonary disease; RD = restrictive disease; NMD = neuromuscular disease; OHS = obesity-hypoventilation syndrome; OL = sleep apnoea syndrome. Mean values and SD of HRQL are given, and differences between COPD and the other groups were compared by the t-test, as values were normally distributed within groups. *p < 0.05; **p < 0.017 (overall p < 0.05 according to Bonferroni correction); ***p < 0.001.

ISSN: 1465-993X