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Table 1 Clinical characteristics of cystic fibrosis patients

From: Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis

Study population (n)

255

Age at enrolment, yrs (mean ± SD)

11.1 ± 5.1

Age at diagnosis, yrs (mean ± SD)

1.4 ± 2.3

Sex, male/female

134/121

CFTR genotype

 

   F508del homozygous

136 (53%)

   F508del compound heterozygous

91 (36%)

   Other mutations

28 (11%)

P. aeruginosa infection at 9 yrs *

63 ± 3%

P. aeruginosa chronic colonization at 9 yrs*

60 ± 3%

Impaired glucose tolerance

21 (8%)

Diabetes

15 (6%)

  1. Abbreviations: yrs: years; P. aeruginosa: Pseudomonas aeruginosa
  2. * Cumulated incidence by Kaplan-Meier estimate