Table 2 Differential cell counts in IS and BAL samples
From: Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD
Variable | COPD smokers | COPD ex-smokers | 'Healthy' smokers | Healthy never-smokers | CS/CE | CS/HS | CS/HN | CE/HS | CE/HN | HS/HN |
|---|---|---|---|---|---|---|---|---|---|---|
Induced sputum | ||||||||||
Neutrophils | 67.7 ± 7.7 | 75.9 ± 9.5 | 22.6 ± 3.3 | 16.1 ± 7.0 | >0.05 | <0.05 | <0.01 | 0.05 | 0.01 | >0.05 |
Eosinophils | 4.5 ± 2.2 | 3.4 ± 1.6 | 1.8 ± 0.4 | 2.3 ± 0.5 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 |
Lymphocytes | 4.7 ± 1.6 | 2.7 ± 0.9 | 6.3 ± 1.1 | 4.9 ± 0.8 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 |
Macrophages | 23.1 ± 7.5 | 18.0 ± 3.5 | 69.3 ± 9.5 | 64.8 ± 10.2 | >0.05 | <0.05 | <0.05 | 0.05 | <0.05 | >0.05 |
BAL | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Recovery of BAL fluid | 43.1 ± 8.3 | 59.3 ± 6.7 | 83.3 ± 6.9 | 81.0 ± 3.8 | <0.05 | <0.05 | <0.05 | <0.05 | <0.05 | >0.05 |
Neutrophils | 17.4 ± 4.8 | 3.2 ± 1.5 | 2.7 ± 0.4 | 1.2 ± 0.5 | <0.01 | 0.05 | <0.01 | >0.05 | 0.01 | <0.01 |
Eosinophils | 0.8 ± 0.3 | 0.8 ± 0.3 | 0.2 ± 0.1 | 0.2 ± 0.1 | >0.05 | >0.05 | >0.05 | >0.05 | <0.05 | >0.05 |
Lymphocytes | 22.6 ± 6.5 | 19.8 ± 3.9 | 24.2 ± 4.5 | 21.0 ± 4.4 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 | >0.05 |
Macrophages | 59.2 ± 6.9 | 76.2 ± 9.3 | 72.9 ± 10.6 | 77.6 ± 10.6 | <0.01 | >0.05 | <0.05 | >0.05 | >0.05 | >0.05 |