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Table 1 Characteristics of subjects

From: Patterns of airway inflammation and MMP-12 expression in smokers and ex-smokers with COPD

Variables

COPD smokers

COPD ex-smokers

'Healthy' smokers

Healthy never-smokers

Subjects (n)

22

17

8

11

Male/Female

22/0

14/3

7/1

4/7

Age (years)

64.2 ± 4.9

62.7 ± 6.3

61.7 ± 6.2

59.8 ± 8.2

Smoking (pack-years)

33.4 ± 5.7

27.9 ± 5.1

28.8 ± 12.1

-

FEV1 (L)

1.5 ± 0.4*#

1.7 ± 0.2*#

3.2 ± 0.6

3.7 ± 0,2

FEV1 (% pred.)

53.3 ± 4.2*#

57.1 ± 4.7*#

109.6 ± 5.3

117.5 ± 4.1

FVC (L)

2.7 ± 0.5*#

2.9 ± 0.4*#

3.0 ± 0.2

3.3 ± 0.2

FVC (% pred.)

69.8 ± 9.1*#

71.7 ± 7.3*#

108.1 ± 8.2

110.0 ± 6.4

FEV1/FVC ratio

50.2 ± 5.9*#

52.5 ± 6.8*#

91.0 ± 4.6

93.5 ± 1.0

  1. Values are mean of percentage ± SEM. *: p < 0.05 compared to healthy never-smokers; #: p < 0.05 compared to 'healthy' smokers