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Table 3 Inhibition of IFN-γ secretion in co-cultures. The effects of 100 nM p38 inhibitor BIRB-796, 100 nM beclomethasone, 500 nM IKK-2 inhibitor V, 100 nM PDE4 inhibitor rolipram, 1 μM PI3 kinase inhibitor and human 10 μg/ml CD40 antibody on secretion of IP-10 from co-cultures.

From: The role of IFN-γ in regulation of IFN-γ-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures

  A549/PBMC + IL-12
BIRB-796 99 (± 0) ***
IKK-2 inh. V 11 (± 9)
Beclomet 98 (± 0) ***
Rolipram 26 (± 7)
PI3 kin. Inh. 77 (± 7)*
CD40 ab 26 (± 11)
  1. Data represents the percentage of inhibition, mean (SEM). ***p < 0.001 and *p < 0.05, ANOVA with Bonferroni's multiple comparison test.