Body composition and functional limitation in COPD

Respiratory Research

Table 4 Body composition and exercise performance on the Six Minute Walk Test among patients with COPD

Measure of body composition	Age adjusted	Age, height, FEV₁/FVC adjusted	Age, height, FEV₁/FVC, race, education, and smoking adjusted
	Mean meters (95% CI)	Mean meters (95% CI)	Mean meters (95% CI)
MEN (n = 143)
Lean/fat ratio	39 (9 to 69)	42 (11 to 72)	40 (9 to 71)
SAD	-29 (-42 to -15)	-34 (-47 to -20)	-34 (-48 to -19)
BMI
Normal weight	Referent	Referent	Referent
Overweight	27 (-171 to 225)	-28 (-225 to 169)	-88 (-295 to 120)
Obese	-264 (-431 to -97)	-263 (-431 to -95)	-269 (-451 to -87)
WOMEN (n = 212)
Lean/fat ratio	140 (82 to 199)	159 (96 to 223)	162 (97 to 228)
SAD	-34 (-43 to -24)	-38 (-48 to -28)	-39 (-49 to -28)
BMI
Normal weight	Referent	Referent	Referent
Overweight	-42 (-202 to 117)	-56 (-217 to 106)	-49 (-214 to 115)
Obese	-340 (-462 to -218)	-392 (-521 to -262)	-398 (-531 to -264)

Results are from separate multivariate linear regression of distance in meters walked in 6 minutes regressed on body composition measures plus covariates.
Lean/fat ratio = derived from bioelectrical impedance. Results are expressed per 0.50 increment in the ratio.
SAD = sagittal abdominal diameter, an estimate of visceral fat. Results are expressed per 1 cm increment.
BMI = body mass index, an estimate of adiposity; normal weight (18.5 to 24.9 kg/m²) overweight = 25.0 to 29.9 kg/m², obese = 30.0 kg/m² or greater; only 9/355 (2.5%) of subjects were in underweight category (< 18.5 kg/m²) so these were included in the normal weight group

ISSN: 1465-993X