IgG | 4 weeks | 1 year |
|---|
| |
nasal booster
|
systemic booster
|
nasal booster
|
systemic booster
|
|---|
Serum
| 6/6 | 6/6 | 6/6 | 6/6 |
BALF
| 4/5 | 6/6 | n.a. | n.a. |
Induced Sputum
| 3/6 | 5/6 | 5/5 | 5/5 |
IgA
|
4 weeks
|
1 year
|
| |
nasal booster
|
systemic booster
|
nasal booster
|
systemic booster
|
Serum | 6/6 | 6/6 | 6/6 | 6/6 |
BALF
| 1/5 | 3/6 | n.a. | n.a. |
Induced Sputum
| 4/6 | 3/6 | 5/5 | 5/5 |
- Responder rates for OprF-OprI-specific IgG (left part of the table) and IgA (right part) antibody formation in serum, pooled bronchoalveolar lavage fluid (BALF), and supernatant of induced sputum (IS) 4 weeks and 1 year after the vaccination. For vaccination schedule refer to Figure legend 1. An antibody response was considered positive, if the post-vaccination ELISA unit was 50% or more above the individual pre-vaccination level. Data are given numbers of individuals with positive response vs. the total number of vaccinees of this group. n.a. = not applicable, since BAL was performed at 4 weeks only.
