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Table 1 Composition of formulations tested in solution tests and in vivo influenza model

From: Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection

Formulation tested

Code

Solution test

in vivo model

PCA/ascorbic acid/phytic acid

PAP

xa

 

PCA/ascorbic acid/zinc acetate dihydrate

PAZ

xa

 

PCA/citric acid/phytic acid

PCP

xa

xa

PCA/ascorbic acid/phytic acid/Carbopol 980

PAPC

 

xa

PCA/ascorbic acid/zinc acetate/Carbopol 980

PAZC

 

xa

PCA/citric acid/phytic acid/Carbopol 980

PCPC

 

xa

PCA/succinic acid/zinc acetate/HPMC

PSZH

xb

 
  1. a Conducted by Retroscreen Virology, London, UK.
  2. b Conducted by ATS Labs, Eagan, MN, USA