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Table 2 Fluorescence values and histological results of all biopsy sites

From: In-vivo kinetics of inhaled 5-Aminolevulinic acid-Induced Protoporphyrin IX fluorescence in bronchial tissue

Pat #

Time after 5-ALA inhalation [min]

Histological result and visual fluorescence

Fluorescence "pathologic tissue" [a.u.] measurement 1–3

Fluorescence "normal tissue" [a.u.] Measurement 1–3

1

135

Sc +

Sqc +

 

5.0

3.7

-

2.7

2.6

-

2

245

Sqc +

  

3.4

-

-

-

-

-

3

75

Sqc +

  

1.0

-

-

0.5

-

-

4

85

Ade +

Ade +

No +

6.9

3.4

1.6

1.0

0.2

2.2

5

345

Inf +

  

1.4

-

-

0.5

-

-

6

225

Met +

Hyp +

 

3.0

6.2

-

1.3

2.8

-

7

135

Hyp +

Hyp -

 

5.2

2.6

-

1.4

1.1

-

8

60

Met +

Sqc +

 

2.7

1.4

-

2.1

0.3

-

9

290

No +

Inf +

Inf +

1.2

3.2

1.7

-

1.6

-

10

195

Hyp +

Sqc +

 

2.5

6.3

-

0.3

1.3

-

11

390

Inf +

Ade +

 

1.2

1.1

-

-

-

-

12

165

Inf +

Met -

Inf -

1.2

0.7

0.8

0.4

0.8

-

13

140

Hyp -

Inf -

Inf -

1.2

1.3

1.4

-

-

0.9

14

195

Hyp +

Hyp +

 

-

-

-

-

-

-

15

210

Dys II +

Dys II +

 

-

-

-

-

-

-

16

180

Sqc +

Inf

 

-

-

-

-

-

-

17

255

Sqc +

Dys III +

 

3.3

3.2

-

2.2

2.2

-

18

180

TBC +

  

3.0

-

-

0.2

-

-

19

210

Sqc +

Sqc +

 

5.0

3.7

-

2.1

2.8

-

  1. Abbreviations: No = normal, Inf = inflammation, TBC = tuberculosis, Hyp = hyperplasia, Met = metaplasia, Dys = dysplasia grading I-III (mild, moderate, severe), Sqc = squamous carcinoma, Sc = small cell carcinoma, Ade = adenocarcinoma, + = fluorescence positive (visually), - = fluorescence negative (visually), a.u. = arbitrary units. Missing values represent measurements with low signal-to-noise ratio.
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Respiratory Research

ISSN: 1465-993X

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