Table 1 List of studied angiogenic and angiostatic mediators in ILDs
From: Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?
Angiogenic mediators |
|---|
CXC chemokines containing the ELR motif |
   • GRO-a/CXCL1 |
   • GRO-b/CXCL2 |
   • GRO-γ/CXCL3 |
   • ENA-78/CXCL5 |
   • GCP-2/CXCL6 |
   • NAP-2/CXCL7 |
   • IL-8/CXCL8 |
Growth Factors |
   • VEGF |
   • bFGF |
Angiostatic mediators |
CXC chemokines that lack the ELR motif |
   • PF-4/CXCL4 |
   • MIG/CXCL9 |
   • IP-10/CXCL10 |
   • ITAC/CXCL11 |
   • CXCL14 |
Growth Factors |
   • PEDF |
Abbreviations: bFGF: basic fibroblast growth factor, GCP: Granulocyte chemotactic protein, GRO: Growth related genes, IP-10:IFN-γ-inducible -protein 10, ITAC: IFN-γ-inducible T-cell a chemoattractant, MIG: Monocyte Induced by interferon gamma-protein, NAP: Neutrophil activating protein, PEDF: Pigment epithelium growth factor, PF: Platelet factor,, VEGF: Vascular growth factor |