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Table 7 Frequency of defensin polymorphisms by racial group.

From: Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

Polymorphism Genotype White (n = 579)† African American (n = 27)† p Value*
DEFA1/DEFA3     
  DEFA1 only 11.1 22.2 0.08
  DEFA1/DEFA3 88.9 77.8  
DEFB1 G-20A     
  GG 30.1 44.4 0.21
  GA 48.5 44.5  
  AA 21.4 11.1  
DEFB1 C-44G     
  CC 64.8 100.0 0.0008
  CG 30.4 0.0  
  GG 4.8 0.0  
DEFB1 G-52A     
  GG 40.9 22.2 0.001
  GA 44.2 37.1  
  AA 14.9 40.7  
  1. Definition of abbreviations: DEFA = alpha-defensin; DEFB = beta-defensin.
  2. * p Value derived from chi-square test.
  3. †Overall observed SNP frequency (%).