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Table 7 Frequency of defensin polymorphisms by racial group.

From: Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

Polymorphism

Genotype

White (n = 579)†

African American (n = 27)†

p Value*

DEFA1/DEFA3

    
 

DEFA1 only

11.1

22.2

0.08

 

DEFA1/DEFA3

88.9

77.8

 

DEFB1 G-20A

    
 

GG

30.1

44.4

0.21

 

GA

48.5

44.5

 
 

AA

21.4

11.1

 

DEFB1 C-44G

    
 

CC

64.8

100.0

0.0008

 

CG

30.4

0.0

 
 

GG

4.8

0.0

 

DEFB1 G-52A

    
 

GG

40.9

22.2

0.001

 

GA

44.2

37.1

 
 

AA

14.9

40.7

 
  1. Definition of abbreviations: DEFA = alpha-defensin; DEFB = beta-defensin.
  2. * p Value derived from chi-square test.
  3. †Overall observed SNP frequency (%).