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Table 1 Biochemical analysis of bronchoalveolar lavage fluid at 24 h of different gas exposure.

From: Inhaled nitric oxide alleviates hyperoxia suppressed phosphatidylcholine synthesis in endotoxin-induced injury in mature rat lungs

Subgroup

TPL (mg/kg)

DSPC (mg/kg)

TP (mg/kg)

DSPC/TP (μg/mg)

C-Air

7.8 ± 1.6

3.4 ± 0.4

19.2 ± 04.9

186 ± 38.9

LPS-Air

6.3 ± 1.6 *

2.7 ± 0.7 **

29.9 ± 6.0 #

89 ± 12.4 ##**

C-ONO

7.4 ± 2.0

3.3 ± 0.5

18.0 ± 3.8

188 ± 22.9

LPS-ONO

5.4 ± 1.2

2.2 ± 0.7

38.3 ± 12.0 ##

63 ± 20.3 ##*

C-O

8.1 ± 1.2

3.3 ± 0.6

19.8 ± 6.3

176 ± 33.4

LPS-O

4.1 ± 0.8 ##

1.6 ± 0.4 ##

46.2 ± 8.8 ##

35.0 ± 3.8 ##

C-NO

7.8 ± 1.8

3.5 ± 0.7

20.2 ± 6.6

179 ± 31.0

LPS-NO

5.9 ± 1.6

2.5 ± 0.8

33.2 ± 6.8 ##

75 ± 14.7 ##**

  1. Definition of subgroups and parameter abbreviations: C, normal control group; LPS, lipopolysaccharides-treated group; Air, room air; NO, 20 ppm nitric oxide; ONO, 95% O2 and 20 ppm NO; O, 95% O2. TPL, total phospholipids; DSPC/TPL, disaturated phosphatidylcholine to TPL ratio; TP, total proteins; DSPC/TP, DSPC to TP ratio. Values represent means ± SD (n = 8). Statistical analysis: # P < 0.05, ## P < 0.01 versus the corresponding C subgroup; * p < 0.05, ** p < 0.01 versus LPS-O.
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Respiratory Research

ISSN: 1465-993X

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