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Table 5 Comparison of first-line resistance levels in Beijing compared to non-Beijing strains (n = 709^)

From: The Directly Observed Therapy Short-Course (DOTS) strategy in Samara Oblast, Russian Federation

Drug

Beijing strain (n = 361)

Non-Beijing strain (n = 348)

OR (95%CI)

RR (95%CI)

RD (95%CI)

 

N resistant

% resistant (95%CI)

N resistant

% resistant (95%CI)

   

Isoniazid*

170

47.1 (48.0–52.3)

53

15.2 (11.7–19.3)

5.0 (3.5–7.1)

3.1 (2.4–4.1)

31.9 (25.2–38.5)

Rifampicin*

140

38.8 (33.9–43.9)

41

11.8 (8.7–15.5)

4.7 (3.2–7.0)

3.3 (2.4–4.5)

27.0 (20.7–33.3)

MDR TB*

127

35.2 (30.4–40.2)

33

9.5 (6.7–12.9)

5.2 (3.4–7.9)

3.7 (2.6–5.3)

25.7 (19.6–31.8)

Streptomycin*

144

39.9 (34.9–45.0)

45

12.9 (9.7–16.8)

4.5 (3.1–6.5)

3.1 (2.3–4.2)

27.0 (20.5–33.4)

Ethambutol*

89

24.7 (20.4–29.3)

26

7.5 (5.0–10.6)

4.1 (2.5–6.5)

3.3 (2.2–5.0)

17.2 (11.7–22.)

  1. * statistically significant difference at p < 0.001
  2. ^ both epidemiological and drug resistance results were available for 709/1042 (68.0%) cultures; 31 cultures were non viable or contaminated; cultures were drawn from all dispensaries and prison facilities in Samara City.