Table 5 Decrease in FEV1 response to fenoterol after terbutaline pre-treatment as compared to placebo pre-treatment. Response was averaged over fenoterol dose 200–3000 μg. Negative numbers indicate an increase in response.
From: Limited β2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics
Decrease in FEV1 (percent points) | ||||
|---|---|---|---|---|
Allelic genotype | Mean | 95% CI | P-value | |
I/III | 0.71 | -1.79 | 3.21 | 0.57 |
III/III | -0.28 | -3.19 | 2.63 | 0.85 |
II/III | 1.84 | -2.16 | 5.84 | 0.36 |
I/I | 3.02 | 0.09 | 5.95 | 0.044 |
I/II | -0.80 | -5.28 | 3.68 | 0.72 |
II/II | 6.04 | -0.18 | 12.26 | 0.057 |