Table 2 Localization of SNPs and delineation of haplotypes of the β2-AR gene in the cohort. The limited haplotypes correspond to the SNPs in boldface. Haplotypes between brackets correspond to those of Drysdale et al.
From: Limited β2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics
Nucleotide: | -1023 | -654 | -468 | -367 | -47 | -20 | 46 | 79 | ||
|---|---|---|---|---|---|---|---|---|---|---|
Alleles | G/A | G/A | C/G | T/C | T/C | T/C | G/A | C/G | ||
Limited Haplotype | n | Frequency (%) | ||||||||
III Arg19Gly16Glu27 (2) | A | G | G | C | C | C | G | G | 39 | 43,3 |
Ia Cys19Arg16Gln27 (4) | G | A | C | T | T | T | A | C | 36 | 40 |
II Cys19 Gly16Gln27 (6) | G | A | C | T | T | T | G | C | 13 | 14,4 |
Ib Cys19Arg16Gln27 (1) | A | G | C | T | T | T | A | C | 1 | 1,1 |
Ic Cys19Arg16Gln27 (x) | G | G | G | T | T | T | A | C | 1 | 1,1 |