| Â | Rest | PI max | R PNS | L PNS | B PNS |
|---|
| Â | cmH2O | cmH2O | cmH2O | cmH2O | cmH2O |
|---|
G I | 1.7 ± 0.6 | 21.5 ± 2.8 | 10.5 ± 1.8 | 9.3 ± 0.8 | 15.7 ± 3.4 |
G II | 2.6 ± 1.1 | 20.5 ± 3.1 | na | 12.4 ± 1.2* | 12.4 ± 1.2 |
G III | 1.7 ± 0.3 | 27.4 ± 4.5* | 6.1 ± 1.2* | 10.6 ± 2.2 | 16.3 ± 2.3 |
G IV | 2.3 ± 0.8 | 27.0 ± 1.0* | 8.7 ± 4.0 | 15.8 ± 4.8* | 16.9 ± 4.7 |
G V | 1.9 ± 0.8 | 20.0 ± 4.7 | 6.4 ± 2.0* | 10.6 ± 2.0 | 11.8 ± 2.2* |
- Values are means ± SD and are expressed in cm H2O. Rest: Esophageal pressure (Pes) during quiet breathing; PImax: Pes during prolonged occlusion tracheostomy cannula; R PNS: Pes obtained by supramaximal stimulation of the right phrenic nerve; L PNS: Pes obtained by supramaximal stimulation of the left phrenic nerve; B PNS: Pes obtained by bilateral supramaximal stimulation of the phrenic nerve; na, not available; *: statistical difference with the healthy control group (GI) (Z > 1.96 or p < 0.05).
- -GI: healthy group control; -GII: section and resection of the entire right phrenic nerve (PN) in the neck (denervated group control); -GIII: the right PN trunk sectioned in the neck below the 6th cervical root and immediately anastomosed to the abductor branch of the right inferior laryngeal nerve (ILN); -GIV: right PN trunk sectioned in the neck below the 6th cervical root and immediately anastomosed to the right ILN; -GV: the right 4th, 5th and 6th (r.C4, r.C5, r.C6) cervical roots sectioned in the neck, r.C4 anastomosed to the abductor branch of the ILN and r.C5 anastomosed to the nerve of the sternothyroid muscle.
