Hazard Ratio | [95% CI] | p value | |
---|---|---|---|
Factors related to severity of CF disease in stable state | |||
Age | 1.02 | [0.91–1.14] | 0.701 |
Sex | 1.39 | [0.69–2.77] | 0.347 |
BMI | 0.95 | [0.80–1.13] | 0.614 |
Diabetes | 0.79 | [0.34–1.85] | 0.595 |
Severity of CFTR genotype | 0.84 | [0.29–2.42] | 0.750 |
P. aeruginosa colonization | 1.49 | [0.40–5.55] | 0.544 |
B. cepacia complex colonization | 1.95 | [0.77–4.89] | 0.153 |
FEV1, % predicted | 0.97 | [0.93–1.02] | 0.289 |
Room air PaO2 | 0.96 | [0.93–0.99] | 0.041 |
Room air PaCO2 | 1.01 | [0.95–1.07] | 0.646 |
Annual FEV1 loss, % predicted/yr | 1.25 | [1.04–1.52] | 0.019 |
Long-term oxygenotherapy | 1.66 | [0.53–5.17] | 0.375 |
Home NIV | 1.19 | [0.30–4.64] | 0.794 |
Factors related to ICU hospitalization | |||
SAPSII | 1.05 | [1.02–1.08] | 0.001 |
PaO2 at entry | 1.004 | [0.999–1.009] | 0.065 |
PaCO2 at entry | 1.01 | [1.01–1.02] | 0.001 |
Initial noninvasive ventilation | 12.78 | [1.63–100.25] | 0.015 |
Initial intubation | 14.57 | [1.42–149.22] | 0.024 |
Intubation during stay | 16.82 | [4.93–57.38] | 0.001 |