Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis

Table 5 Diagnostic accuracy of the predictors of alveolitis

	AUC (95% CI)	p	Cut-off value	Se(%)	Sp (%)
FVC	0.145 (-0.003 – 0.292)	0.000	80.5	77.8	100.0
DLCO	0.199 (0.058 – 0.340)	0.001	50.0	72.2	70.8
IL-6	0.694 (0.524 – 0.864)	0.045	0.75	80.0	60.9
Skin score	0.650 (0.473 – 0.826)	0.109	14.5	58.8	78.3
Alveolar score on HRCT	0.742 (0.591 – 0.893)	0.008	6.5	66.7	75.0

AUC: area under curve ROC; FVC: forced vital capacity; DLCO: diffusing capacity for carbon monoxide; HRCT: high resolution computed tomography.

ISSN: 1465-993X