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Table 3 Functional, radiological and BAL analysis.

From: Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis

 

100 SSc patients

FVC % mean ± sd

100.1 ± 22.1

≤ 79% n (%)

16 (16.0%)

≤ 69% n (%)

12 (12.0%)

≤ 49% n (%)

1 (1.0%)

DLCO % mean ± sd

59.4 ± 17.3

≤ 79% n (%)

90 (90.0%)

≤ 69% n (%)

83 (83.0%)

≤ 49% n (%)

29 (29.0%)

PASP ≥ 40 mmHg n (%)*

11 (11.8%)*

≥ 60 mmHg n (%)*

2 (2.2%)*

HRCT: interstitial score ≥ 2, n (%)*

87 (93.5%)*

mean total score ± sd

3.1 ± 4.2

HRCT: alveolar score ≥ 2, n (%)*

55 (59.1%)*

mean total score ± sd

5.7 ± 2.6

BAL: alveolitis n (%)**

16 (38.1%)**

N ≥ 5 % n (%)**

11 (68.8%)**

N ≥ 5 % and L ≥ 15 % n (%)**

2 (12.5%)**

N ≥ 5 % and E ≥ 5 % n (%)**

2 (12.5%)**

N ≥ 5 %, L ≥ 15 % and E ≥ 5 % n (%)**

1 (6.2%)**

N < 5 % and L ≥ 15 % and/or E ≥ 5 % n (%)**

0 (0.0%)**

BAL with positive cultures n (%)**

10 (23.8%)**

  1. BAL: bronchoalveolar lavage; SSC: systemic sclerosis; FVC: forced vital capacity; DLCO: diffusing capacity for carbon monoxide; PASP: pulmonary artery systolic pressure; HRCT: high resolution computed tomography; N: neutrophils; L: lymphocytes; E: eosinophils.
  2. *Echocardiography and HRCT performed in 93 SSc patients
  3. ** BAL performed in 42 SSc patients giving their informed consent