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Table 3 Functional, radiological and BAL analysis.

From: Functional, radiological and biological markers of alveolitis and infections of the lower respiratory tract in patients with systemic sclerosis

  100 SSc patients
FVC % mean ± sd 100.1 ± 22.1
≤ 79% n (%) 16 (16.0%)
≤ 69% n (%) 12 (12.0%)
≤ 49% n (%) 1 (1.0%)
DLCO % mean ± sd 59.4 ± 17.3
≤ 79% n (%) 90 (90.0%)
≤ 69% n (%) 83 (83.0%)
≤ 49% n (%) 29 (29.0%)
PASP ≥ 40 mmHg n (%)* 11 (11.8%)*
≥ 60 mmHg n (%)* 2 (2.2%)*
HRCT: interstitial score ≥ 2, n (%)* 87 (93.5%)*
mean total score ± sd 3.1 ± 4.2
HRCT: alveolar score ≥ 2, n (%)* 55 (59.1%)*
mean total score ± sd 5.7 ± 2.6
BAL: alveolitis n (%)** 16 (38.1%)**
N ≥ 5 % n (%)** 11 (68.8%)**
N ≥ 5 % and L ≥ 15 % n (%)** 2 (12.5%)**
N ≥ 5 % and E ≥ 5 % n (%)** 2 (12.5%)**
N ≥ 5 %, L ≥ 15 % and E ≥ 5 % n (%)** 1 (6.2%)**
N < 5 % and L ≥ 15 % and/or E ≥ 5 % n (%)** 0 (0.0%)**
BAL with positive cultures n (%)** 10 (23.8%)**
  1. BAL: bronchoalveolar lavage; SSC: systemic sclerosis; FVC: forced vital capacity; DLCO: diffusing capacity for carbon monoxide; PASP: pulmonary artery systolic pressure; HRCT: high resolution computed tomography; N: neutrophils; L: lymphocytes; E: eosinophils.
  2. *Echocardiography and HRCT performed in 93 SSc patients
  3. ** BAL performed in 42 SSc patients giving their informed consent