Figure 3
From: PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse
MMP-2 (76 kDa) and MMP-9 (105 kDa) activity in BALF from PPARα+/+(+/+) and PPARα-/-(-/-) mice exposed to LPS or saline. Upper panel shows gelatin zymogram from two representative animals in each group. Lower panel shows data of all animals in each group (n = 10–13) expressed as mean ± SEM. Statistically significant differences at α = 0.05: (*) when compared to PPARα+/+ mice treated with saline; (#) when compared to PPARα-/- mice treated with saline; and ($) when compared to PPARα+/+ mice treated with LPS.