Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation

Table 1 Viable, apoptotic, necrotic and cytolytic eosinophils in mice with OVA-induced established lung tissue eosinophilia.

	Viable eosinophils ^A	Apoptotic eosinophils^A		Cytolytic eosinphils^A	Neutrophils^B
		Intact	Necrotic
OVA/control 8 h	100	0	0	0	3 ± 1
OVA/FAS 8 h	69 ± 7	19 ± 5	8 ± 3	4 ± 1	12 ± 4
OVA/control 24 h	100	0	0	0	5 ± 0.5
OVA/FAS 24 h	70 ± 4	13 ± 3	15 ± 2	2 ± 0.7	24 ± 2

^A = Eosinophil phenotypes are presented as % of total number of eosinophils in each transmission electron microscopy grid (n = 8).
^B = Number of neutrophils occurring in each grid (n = 8).

ISSN: 1465-993X