Figure 1From: Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammationStudy design. All animals were immunized with OVA and 14 days later exposed to aerosol challenge with OVA for 7 days to establish tissue and lumen eosinophilia. Treatment with anti-Fas mAb or isotype control IgG was administered intra-nasally at day 22 and outcome measurements including BAL and tissue sampling were made at 8 and 24 h after treatment.Back to article page