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Table 3 Quality of life as assessed on the St George's Hospital Respiratory

From: Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

 

Losartan

Placebo

 
 

Baseline

(n = 19)

End of study

(n = 15)

Change

Baseline

(n = 20)

End of study

(n = 18)

Change

p-value*

Overall score

66 (18)

60 (15)

-3.6 (9.2)

65 (14)

66 (19)

+1.7 (9.2)

0.11

Symptom component

72 (17)

67 (22)

-2.7 (15.5)

71 (16)

66 (20)

-5.6 (16.3)

0.61

Activity component

76 (17)

74 (13)

-1.2 (10.8)

77 (17)

83 (19)

+7.5 (14.1)

0.06

Impact component

57 (23)

49 (18)

-5.2 (12.6)

56 (17)

56 (22)

+0.7 (13.1)

0.20

  1. *Between group p-value for the difference in change from baseline.
  2. NB. Improvement in QoL is denoted by a reduction in score.