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Table 3 Quality of life as assessed on the St George's Hospital Respiratory

From: Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

  Losartan Placebo  
  Baseline
(n = 19)
End of study
(n = 15)
Change Baseline
(n = 20)
End of study
(n = 18)
Change p-value*
Overall score 66 (18) 60 (15) -3.6 (9.2) 65 (14) 66 (19) +1.7 (9.2) 0.11
Symptom component 72 (17) 67 (22) -2.7 (15.5) 71 (16) 66 (20) -5.6 (16.3) 0.61
Activity component 76 (17) 74 (13) -1.2 (10.8) 77 (17) 83 (19) +7.5 (14.1) 0.06
Impact component 57 (23) 49 (18) -5.2 (12.6) 56 (17) 56 (22) +0.7 (13.1) 0.20
  1. *Between group p-value for the difference in change from baseline.
  2. NB. Improvement in QoL is denoted by a reduction in score.