From: Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease
 | Losartan (n = 20) | Placebo (n = 20) |
---|---|---|
 | Demography | |
Male:Female | 9:11 | 10:10 |
Age (years) | 68 (8.4) | 66 (7.3) |
 | Spirometry | |
FEV1 (litres) | 0.85 (0.40) | 0.82 (0.38) |
FVC (litres) | 2.5 (0.9) | 2.5 (0.9) |
Percent predicted FEV1 (%) | 37 (19) | 33 (14) |
 | Echo findings | |
TTPG (mmHg) | 42.8 (8.8) | 43.4 (9.9) |
Estimated right atrial pressure (mmHg) | 4.0 (0.8) | 4.11 (0.9) |
 | Exercise capacity | |
Number of shuttles | 18.3 (9.3) | 18.2 (7.6) |
Breathlessness score | 6.4 (1.9) | 6.7 (2.0) |