Figure 3From: Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitorsInfluence of iloprost nebulization and its combination with sub-threshold doses of intravenous PDE inhibitors on U46619-elicted pulmonary hypertension. Decrease in pulmonary vascular resistance (PVR, in %) at the end of the nebulization period is given (mean ± SEM of 8 independent experiments each). The PDE inhibitors were pre-applied as short-term infusion as follows: 200 μg/kg × min 8-Methoxymethyl-IBMX, 1 μg/kg × min sildenafil, 5 μg/kg × min motapizone. *, p < 0.05 as compared to pre-nebulization value.Back to article page