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Table 2 Surface molecules on repeatedly stimulated CD8+ T cells*

From: IL-4 increases type 2, but not type 1, cytokine production in CD8+ T cells from mild atopic asthmatics

IL-4

-

+

P †

CD3+

97 ± 1

98 ± 0.5

NS

CD3+CD8+CD4-

97 ± 1

97 ± 1

NS

CD3+CD4+CD8-

0.2 ± 0.2

0.3 ± 0.2

NS

CD3+CD4-CD8-

2 ± 1

2 ± 1

NS

CD3+CD4+CD8+

7 ± 6

4 ± 1

NS

CD3+CD8+

   

CD25

53 ± 9

68 ± 9

NS

CD30

23 ± 7

40 ± 6

0.07

CD40L

14.5 ± 5

14.5 ± 6

NS

VLA-4#

444 ± 97

283 ± 72

0.02

LFA-1#

280 ± 51

194 ± 25

0.05

ICAM-1#

37 ± 10

27 ± 7

0.06

  1. *frequency of positive cells or #mean fluorescence intensity of surface antigens after two rounds of stimulation of CD8+ T cells from atopic asthmatic subjects (mean ± SEM; n = 7; NS, nonsignificant).
  2. † comparison between IL-4-treated and -untreated cells (paired Student's t test)
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Respiratory Research

ISSN: 1465-993X

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