Table 1 Patient Characteristics
From: Expression of HSP47 in Usual Interstitial Pneumonia and Nonspecific Interstitial Pneumonia
Idiopathic UIP | CVD-associated UIP | Idiopathic NSIP | p value | |
|---|---|---|---|---|
Age (years) | 64 (34–72) | 44 (38–63) | 58 (28–75) | 0.06 |
Sex (male/female) | 17/2 | 1/6 | 5/11 | 0.0002 |
Smoking (none/ex/smoke) | 6/7/6 | 5/2/0 | 10/3/2 | 0.15 |
Symptom onset (months) | 9 (5–38) | 12 (4–35) | 6 (1–74) | 0.44 |
Spirometry: | ||||
VC (L) | 2.63 (1.28–3.81) | 2.01 (1.34–2.63) | 2.50 (1.11–3.39) | 0.10 |
predicted VC (%) | 78.6 (55.8–117.0) | 67.8 (53.5–112.3) | 79.9 (50.0–108.1) | 0.59 |
FEV1 (L) | 2.18 (1.08–2.81) | 1.67 (1.13–2.28) | 1.72 (0.99–2.98) | 0.05 |
predicted FEV (%) | 84.10 (65.5–90.6) | 84.3 (78.1–94.6) | 80.79 (51.0–96.2) | 0.19 |
Gas exchange: | ||||
DLco (ml/min/mmHg) | 9.13 (6.5–14.65) | 9.94 (3.96–20.27) | 11.45 (6.0–19.85) | 0.35 |
predicted DLco (%) | 49.00 (37.2–97.3) | 43.80 (25.2–61.4) | 57.85 (44.7–109.3) | 0.05 |
Lung volume: | ||||
predicted TLC (%) | 62.45 (45.2–96.7) | 79.90 (58.9–107.6) | 71.55 (62.9–112.4) | 0.04 |
TLC (L) | 3.52 (1.78–5.39) | 3.07 (2.0–4.0) | 3.83 (1.8–8.8) | 0.41 |
Arterial blood gases: | ||||
PaO2 (mmHg) | 82.5 (58.3–108.0) | 89.2 (40.5–97.5) | 83.4 (67.0–92.9) | 0.43 |