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Table 1 Patient Characteristics

From: Expression of HSP47 in Usual Interstitial Pneumonia and Nonspecific Interstitial Pneumonia

  Idiopathic UIP CVD-associated UIP Idiopathic NSIP p value
Age (years) 64 (34–72) 44 (38–63) 58 (28–75) 0.06
Sex (male/female) 17/2 1/6 5/11 0.0002
Smoking (none/ex/smoke) 6/7/6 5/2/0 10/3/2 0.15
Symptom onset (months) 9 (5–38) 12 (4–35) 6 (1–74) 0.44
Spirometry:     
VC (L) 2.63 (1.28–3.81) 2.01 (1.34–2.63) 2.50 (1.11–3.39) 0.10
predicted VC (%) 78.6 (55.8–117.0) 67.8 (53.5–112.3) 79.9 (50.0–108.1) 0.59
FEV1 (L) 2.18 (1.08–2.81) 1.67 (1.13–2.28) 1.72 (0.99–2.98) 0.05
predicted FEV (%) 84.10 (65.5–90.6) 84.3 (78.1–94.6) 80.79 (51.0–96.2) 0.19
Gas exchange:     
DLco (ml/min/mmHg) 9.13 (6.5–14.65) 9.94 (3.96–20.27) 11.45 (6.0–19.85) 0.35
predicted DLco (%) 49.00 (37.2–97.3) 43.80 (25.2–61.4) 57.85 (44.7–109.3) 0.05
Lung volume:     
predicted TLC (%) 62.45 (45.2–96.7) 79.90 (58.9–107.6) 71.55 (62.9–112.4) 0.04
TLC (L) 3.52 (1.78–5.39) 3.07 (2.0–4.0) 3.83 (1.8–8.8) 0.41
Arterial blood gases:     
PaO2 (mmHg) 82.5 (58.3–108.0) 89.2 (40.5–97.5) 83.4 (67.0–92.9) 0.43
  1. Data are median (range).
  2. α-SMA = α-smooth muscle actin; CVD = collagen vascular disease; DLco = diffusing capacity for carbon monoxide; HSP47 = heat shock protein 47; NSIP = nonspecific interstitial pneumonia; Symptom onset = period from the onset to the surgical lung biopsy; TLC = total lung capacity; UIP = usual interstitial pneumonia; VC = vital capacity.