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Table 2 Baseline characteristics and genotype frequencies for the 6 SNPs in both cohorts.

From: Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma

   Adult Study N = 401   CAMP N = 652  
Age, mean(sd)   39.2 (13.7)   8.9 (2.1)  
Gender, male, n(%)   171 (42.8)   393 (60.3)  
FEV1 (%predicted), mean (sd)   71.7 (12.8)   94.3 (14.2)  
Number of positive skin tests, median (minimum, maximum)   ---   4 (0, 18)  
Eosinophil count, geometric mean (sd)   ---   5.86 (2.06)  
IgE, geometric mean (sd)   ---   404.0 (4.9)  
Paternal asthma, n(%)   ---   125 (19.2)  
Maternal asthma, n(%)   ---   164 (25.2)  
Maternal cigarette smoking during pregnancy, n(%)   ---   88 (13.5)  
SNP genotypes, n(%)    HWE p-value   HWE p-value
G3363a16 GG 145 (36.2)   245 (37.6)  
  GT 153 (38.0) 0.6 291 (44.6) 0.7
  TT 46 (11.5)   80 (12.3)  
  missing 57 (14.2)   36 (5.5)  
G3363a3 GG 342 (85.2)   582 (89.3)  
  GA 1 (0.2) 0.004 2 (0.3) 1.0
  AA 1 (0.2)   0  
  missing 57 (14.2)   68 (10.4)  
G3363a4 GG 137 (34.0)   218 (33.4)  
  GC 175 (43.8) 0.3 291 (44.6) 0.5
  CC 70 (17.5)   85 (13.0)  
  missing 19 (4.8)   58 (8.9)  
rs1026916 GG 164 (41.0)   227 (34.8)  
  GA 181 (45.0) 0.8 233 (35.7) 0.2
  AA 52 (13.0)   74 (11.3)  
  missing 4 (1.0)   118 (18.1)  
rs1905340 CC 203 (50.8)   254 (39.0)  
  CA 159 (39.5) 1.0 191 (29.3) 0.6
  AA 30 (7.5)   41 (6.3)  
  missing    166 (25.5)  
rs957971 CC 156 (39.0)   242 (37.1)  
  CG 172 (42.8) 0.6 260 (39.9) 1.0
  GG 54 (13.5)   70 (10.7)  
  missing    80 (12.3)