Table 2 Univariate and multivariate analysis: predictors based on presence of virus particle and lung involvement in patients with SARS.
Factor | Low HRCT score and Absence of virus particle (n = 5) no. (%) | High HRCT score and Presence of virus particle (n = 7) no. (%) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
P value | Odd ratio | 95% confidence interval | P value | |||
Age, year | 25.6 ± 4.2 | 34.9 ± 2.9 | 0.09 | - | - | - |
Female gender | 5 (100%) | 4 (57.1%) | 0.09 | 1.75 | 0.92–3.32 | - |
Titer of Anti-CoV IgG (OD) * | 0.8 ± 0.2 | 1.3 ± 0.1 | 0.04 | - | - | 1.0 |
Days of fever | 4.2 ± 0.5 | 11.0 ± 1.0 | 0.0003 | - | - | 0.011 |
Positive PCR | 2 (28.6%) | 5 (71.4%) | 0.276 | 3.75 | 0.33–42.47 | - |
Use of ribavirin | 4 (57.1%) | 6 (85.7%) | 0.79 | 1.50 | 0.71–31.58 | - |
Use of IVIG | 4 (57.1%) | 6 (85.7%) | 0.79 | 1.50 | 0.71–31.58 | - |
Pulse corticosteroid therapy | 0 (0%) | 4 (57.1%) | 0.04 | 2.33 | 0.99–5.49 | 0.004 |
Maintenance corticosteroid therapy | 0 (0%) | 3 (42.9%) | 0.09 | 1.75 | 0.92–3.32 | - |
Need for intubation | 1 (14.3%) | 1 (14.3%) | 0.79 | 0.67 | 0.03–14.03 | - |