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Table 2 Inflammation in bronchial biopsies from smokers with COPD and asymptomatic smokers

From: Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers

  Total COPD Symptomatic smokers Asymptomatic smokers
  GOLD I-III GOLD 0  
Biopsies, n 19 8 24
   CD3, %positive area 1.05 (0.2–9.24) 0.68 (0.19–1.7) 0.76 (0.17–2.4)
   CD4, %positive area 0.041 (0.01–0.57) 0.073 (0–0.18) 0.04 (0–0.15)
   CD8, %positive area 0.27 (0.03–2.55) 0.19 (0.02–1.53) 0.33 (0.3–1.25)
   CD4/CD8 ratio 0.19 (0.1–4.4) 0.39 (0.04–1.2) 0.18 (0–0.91)
   CD20, %positive area 0.003 (0–3.40) 0.003 (0–0.23) 0.005 (0–0.12)
   NP57, %positive area 0.025 (0–0.13) 0.05 (0–0.23) 0.021 (0–0.36)
   CD68, %positive area 0.035 (0–0.21) 0.056 (0–0.16) 0.041 (0–0.32)
   EG2, %positive area 0.021 (0–0.31) 0.049 (0–0.15) 0.063 (0–0.59)
   AA1, %positive area 0.15 (0.01–0.91) 0.22 (0–0.41) 0.22 (0.1–1.16)
  1. Values expressed in median (range). Abbreviations: CD20 = B-cell marker, NP57 = neutrophil elastase, CD68 = macrophages, EG2 = eosinophils, AA1 = mast cell tryptase.