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Table 2 IC50 values for the inhibition of cytokine mRNA synthesis by combined administration of MAPK inhibitors in vitro. IC50values were calculated from data shown in Figure 8.

From: Inhibitors of mitogen-activated protein kinases differentially regulate costimulated T cell cytokine production and mouse airway eosinophilia

μM IFNγ (U0126) IFNγ (U0126+SB203580) IL-13 (U0126) IL-13 (U0126+SB203580)
α-CD3/B7-2 0.29 0.68 0.28 0.97
α-CD3/B7-H2 0.19 1.14 0.21 0.73