Occupational risk of tuberculosis transmission in a low incidence area

Respiratory Research

Table 2 Health-care work and clustering (multivariate analysis).

Variable	Non-clustered TB		Clustered TB		Crude OR	95% CI	Adj. OR^b	95% CI
	N ^a	%	N ^a	%
Health-care worker
No	545	99.6	269	97.1	1.0	-	1.0	-
Yes	2	0.4	8	2.9	8.1	1.7–38.4	17.9	3.6–89.3
AIDS
No	520	95.1	256	92.4	1.0	-	1.0	-
Yes	27	4.9	21	7.6	1.6	0.9–2.8	0.8	0.4–1.8
Foreign-born
No	284	51.9	185	66.8	1.0	-	1.0	-
Yes	263	48.1	92	33.2	0.5	0.4–0.7	0.5	0.3–0.7
Sex
Female	221	40.4	90	32.5	1.0	-	1.0	-
Male	326	59.6	187	67.5	1.4	1.0–1.9	1.1	0.8–1.6
Drug abuse
No	517	94.5	237	85.6	1.0	-	1.0	-
Yes	30	5.5	40	14.4	2.9	1.8–4.8	1.7	1.0–3.1
Alcohol abuse
No	468	85.6	164	59.2	1.0	-	1.0	-
Yes	79	14.4	113	40.8	4.1	2.9–5.7	2.6	1.7–3.8
Homelessness
No	510	93.2	249	89.9	1.0	-	1.0	-
Yes	37	6.8	28	10.1	1.6	0.9–2.6	0.9	0.5–1.7
History of contact tracing
No	505	92.3	211	76.2	1.0	-	1.0	-
Yes	42	7.7	66	23.8	3.8	2.5–5.7	2.8	1.7–4.6
Sputum smear positivity
No	377	68.9	161	58.1	1.0	-	1.0	-
Yes	170	31.1	116	41.9	1.6	1.2–2.2	1.2	0.9–1.8
Previous history of TB
No	485	88.7	234	84.5	1.0	-	1.0	-
Yes	62	11.3	43	15.5	1.4	0.9–2.2	1.7	1.0–2.7
Unemployment
No	441	80.6	114	41.2	1.0	-	1.0	-
Yes	106	19.4	163	58.8	5.9	4.3–8.2	5.2	3.6–7.5
Latency period from first symptoms to TB diagnosis
< 6 months	432	79.0	156	56.3	1.0	-	1.0	-
≥ 6 months; <12 months	95	17.4	78	28.2	2.3	1.6–3.2	6.0	3.4–10.4
≥ 12 months	20	3.7	43	15.5	2.6	1.7–3.8	7.5	3.7–13.9

^a TB patients < 16 years (n = 22) excluded from the analysis
^b Adjusted for foreign birth; unemployment; alcohol abuse; drug addiction; and the latency period between first symptoms and TB diagnosis; the odds ratios for homelessness and previous history of TB are additionally adjusted for history of contact tracing; the odds ratio for drug addiction is additionally adjusted for AIDS

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