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Table 1 Univariate analysis of risk factors for patients belonging to IS6110 RFLP clusters

From: Occupational risk of tuberculosis transmission in a low incidence area

Characteristic Non-cluster group Cluster group All patients p
  (N = 562) (N = 286) (N = 848)  
Age (yr) mean ± SD 44.9 ± 19.7 43.2 ± 17.2 44.4 ± 18.9 n.s.
AIDS (n, %) 27 (4.8) 21 (7.3) 48(5.7) n.s.
Resistance to any drug (n, %) 52 (9.3) 11 (3.8) 63 (7.4) 0.005
MDR (n, %) 6 (1.1) 4 (1.4) 10 (1.2) n.s.
Foreign-born (n, %) 270 (48.0) 96 (33.6) 366 (43.2) <0.001
Male (n, %) 335 (59.6) 190 (66.4) 525 (61.9) n.s.
Female (n, %) 227(40.4) 96 (33.6) 323 (38.1) n.s.
Drug abuse (n, %) 30 (5.3) 40 (14.0) 70 (8.3) <0.001
Alcohol abuse (n, %) 80 (14.2) 113 (39.5) 193 (22.8) <0.001
Homelessness (n, %) 41 (7.3) 29 (10.1) 70 (8.3) n.s.
History of contact tracing (n, %) 42 (7.5) 70 (24.5) 112 (13.2) <0.001
Site of tuberculosis     
   - Pulmonary (n, %) 513 (91.3) 268 (93.7) 781 (92.1) n.s.
   - Extrapulmonary (n, %) 49 (8.7) 18 (6.3) 67 (7.9) n.s.
   - Cavitary disease (n, %) 109 (19.4) 93 (32.5) 202 (23.8) <0.001
Sputum smear positivity (n, %) 170 (30.2) 118 (41.3) 288 (34.0) 0.001
Previous history of Tb (n, %) 62 (11.0) 43 (15.0) 105 (12.4) n.s.
Diagnosis due to symptoms (n, %) 492 (87.5) 186 (65.0) 678 (80.0) <0.001
Unemployment (n, %) 108 (19.2) 163 (57.0) 271 (32.0) <0.001
Contact persons with disease (n, %) 5 (8.9) 60 (21.0) 65 (7.7) <0.001
Diagnosis due to contact tracing (n, %) 8 (1.4) 30 (10.5) 38 (4.5) <0.001
Health-care worker (n, %) 2 (0.4) 8 (2.8) 10 (1.2) <0.004
Latency from first symptoms to diagnosis     
< 6 months (n, %) 444 (79.0) 164 (57.3) 608 (71.7) <0.001
>= 6 months; < 12 months (n, %) 98 (17.4) 79 (27.6) 177 (20.9) <0.001
>= 12 months (n, %) 20 (3.6) 43 (15.0) 63 (7.4) <0.001
  1. n.s., not significant