Table 1 Univariate analysis of risk factors for patients belonging to IS6110 RFLP clusters
From: Occupational risk of tuberculosis transmission in a low incidence area
Characteristic | Non-cluster group | Cluster group | All patients | p |
|---|---|---|---|---|
(N = 562) | (N = 286) | (N = 848) | ||
Age (yr) mean ± SD | 44.9 ± 19.7 | 43.2 ± 17.2 | 44.4 ± 18.9 | n.s. |
AIDS (n, %) | 27 (4.8) | 21 (7.3) | 48(5.7) | n.s. |
Resistance to any drug (n, %) | 52 (9.3) | 11 (3.8) | 63 (7.4) | 0.005 |
MDR (n, %) | 6 (1.1) | 4 (1.4) | 10 (1.2) | n.s. |
Foreign-born (n, %) | 270 (48.0) | 96 (33.6) | 366 (43.2) | <0.001 |
Male (n, %) | 335 (59.6) | 190 (66.4) | 525 (61.9) | n.s. |
Female (n, %) | 227(40.4) | 96 (33.6) | 323 (38.1) | n.s. |
Drug abuse (n, %) | 30 (5.3) | 40 (14.0) | 70 (8.3) | <0.001 |
Alcohol abuse (n, %) | 80 (14.2) | 113 (39.5) | 193 (22.8) | <0.001 |
Homelessness (n, %) | 41 (7.3) | 29 (10.1) | 70 (8.3) | n.s. |
History of contact tracing (n, %) | 42 (7.5) | 70 (24.5) | 112 (13.2) | <0.001 |
Site of tuberculosis | ||||
- Pulmonary (n, %) | 513 (91.3) | 268 (93.7) | 781 (92.1) | n.s. |
- Extrapulmonary (n, %) | 49 (8.7) | 18 (6.3) | 67 (7.9) | n.s. |
- Cavitary disease (n, %) | 109 (19.4) | 93 (32.5) | 202 (23.8) | <0.001 |
Sputum smear positivity (n, %) | 170 (30.2) | 118 (41.3) | 288 (34.0) | 0.001 |
Previous history of Tb (n, %) | 62 (11.0) | 43 (15.0) | 105 (12.4) | n.s. |
Diagnosis due to symptoms (n, %) | 492 (87.5) | 186 (65.0) | 678 (80.0) | <0.001 |
Unemployment (n, %) | 108 (19.2) | 163 (57.0) | 271 (32.0) | <0.001 |
Contact persons with disease (n, %) | 5 (8.9) | 60 (21.0) | 65 (7.7) | <0.001 |
Diagnosis due to contact tracing (n, %) | 8 (1.4) | 30 (10.5) | 38 (4.5) | <0.001 |
Health-care worker (n, %) | 2 (0.4) | 8 (2.8) | 10 (1.2) | <0.004 |
Latency from first symptoms to diagnosis | ||||
< 6 months (n, %) | 444 (79.0) | 164 (57.3) | 608 (71.7) | <0.001 |
>= 6 months; < 12 months (n, %) | 98 (17.4) | 79 (27.6) | 177 (20.9) | <0.001 |
>= 12 months (n, %) | 20 (3.6) | 43 (15.0) | 63 (7.4) | <0.001 |