Figure 4From: Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injuryVentilatory responses before and after hyperoxia, and during recovery. Minute ventilation (VE) in response to decreasing levels of inspired O2. In each one of the three conditions, mean values (± SD) of VE in IGF-1R+/+ and IGF-1Rneo/- mice were recorded under 90% O2, 21% O2 and at two levels of hypoxia (12% and 10% O2). Values with asterisks are significantly different from control values at 90% O2. Crosses indicate significant differences from normoxic control values, and asterisks indicate significant differences between IGF-1R+/+ and IGF-1Rneo/- mice; P < 0.05.Back to article page