Figure 1From: Arginase attenuates inhibitory nonadrenergic noncholinergic nerve-induced nitric oxide generation and airway smooth muscle relaxationRole of NO and arginase in iNANC nerve-induced relaxation of guinea pig tracheal smooth muscle. Electrical field stimulation-induced relaxation of precontracted guinea pig tracheal open-ring preparations in the absence and presence of the NOS inhibitor L-NNA (100 μM), the arginase inhibitor nor-NOHA (10 μM) or a combination of both inhibitors. Results are means ± s.e.m. of 8 experiments. *P < 0.05 and **P < 0.01 compared to control, †P < 0.05 and ‡P < 0.01 compared to nor-NOHA-treated.Back to article page