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Table 2 Summary of the data on analysis of MAPK ERK1/2, p38 and JNK in NCI-H292 cells following exposure to CSC.

From: Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione

   Treatmentb
MAPK Time a medium TGF-α TNF-α CSC (AU/ml)
      10 5 1
ERK1/2 15 min - + ± + + +
  1 hour - + ± + + +
  6 hours - + - + + +
  24 hours - + - - - +
p38 10 min - - + + + -
  1 hour - - ± + + -
  6 hours - - - ++ ++ -
  24 hours - - - - - -
JNK 10 min - - - - - -
  1 hour - - - + ± -
  6 hours - - - ++ + -
  24 hours - - - - - -
  1. a Cells were exposed to the various treatments for the indicated time periods. b The degree of phosphorylation of the three MAPK studied is indicated by the symbol.