Respiratory Research

Table 2 Summary of the data on analysis of MAPK ERK1/2, p38 and JNK in NCI-H292 cells following exposure to CSC.

From: Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione

		Treatment^b
MAPK	Time ^a	medium	TGF-α	TNF-α	CSC (AU/ml)
					10	5	1
ERK1/2	15 min	-	+	±	+	+	+
	1 hour	-	+	±	+	+	+
	6 hours	-	+	-	+	+	+
	24 hours	-	+	-	-	-	+
p38	10 min	-	-	+	+	+	-
	1 hour	-	-	±	+	+	-
	6 hours	-	-	-	++	++	-
	24 hours	-	-	-	-	-	-
JNK	10 min	-	-	-	-	-	-
	1 hour	-	-	-	+	±	-
	6 hours	-	-	-	++	+	-
	24 hours	-	-	-	-	-	-

^a Cells were exposed to the various treatments for the indicated time periods. ^b The degree of phosphorylation of the three MAPK studied is indicated by the symbol.

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ISSN: 1465-993X

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