Figure 3

Cholinergic AR. Magnitudes of cholinergic AHR, 48 h after EAR, expressed as PD50 values, which is the dose of MCh required to reduce either GL, Cdyn or EF₅₀ to 50 % of their respective baseline values) of invasively measured GL, Cdyn and EF₅₀ (A) as well as of noninvasively recorded EF₅₀ (B). Allergic mice (black columns) showed significantly lower PD50 values compared with controls (white columns). Baseline values were not significantly different from initial baseline values 48 h before and were within the means ± SD as listed in Table 1. Values are means ± SE, n = 8 per group, *p < 0.05 vs. control.