Table 2 Effect of small aggregates (SA) or serum on the surface activity of a well functioning proving surfactant, assessed in a pulsating bubble surfactometer and in a capillary surfactometer
From: Sequential analysis of surfactant, lung function and inflammation in cystic fibrosis patients
Pulsating bubble surfactometer | P | Capillary surfactometer | P | |
|---|---|---|---|---|
Minimal surface tension (mN/m) | % open | |||
Bovine surfactant | 2.3 (0.0 – 3.50) 5 | 100.0 (99.9 – 100.0) 5 | ||
+ 1.5 g/l SA protein | 2.3 (1.5 – 6.6) 5 | ns | 3.35 (0.2 – 10.3) 5 | ns |
+ 1.5 g/l serum protein | 1.9 (1.1 – 8.6) 6 | 0.95 (0.1 – 8.5) 6 | ||
+ 4.5 g/l SA protein | 8.6 (2.3 – 24.6) 5 | ns | 1.03 (0.6 – 2.3) 5 | ns |
+ 4.5 g/l serum protein | 19.6 (1.5 – 31.9) 7 | 4.83 (0.3 – 35.5) 7 |