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Table 1 Surfactant proteins (SP-) A, B, C and D, total proteins and phospholipids in three consecutive bronchoalveolar lavages (BAL) in patients with cystic fibrosis over a 3 year period

From: Sequential analysis of surfactant, lung function and inflammation in cystic fibrosis patients

 

1. BAL at start of the study

2. BAL after 1.5 years

3. BAL after 3 years

SP-A (ng/ml)

5312.0 (2409.0 – 13218.0)

5580.0 (1334.0 – 13048.0)

3782.0 (128.6 – 13624.0)

SP-B (ng/ml)

397.5 (247.2 – 1219.0)

897.5 (472.5 – 1252.0)†

847.0 (375.5 – 1602.0) **

SP-C (ng/ml)

635.0 (37.0 – 1557.0)

638.7 (391.5 – 2012.0)

581.2 (15.5 – 1489.0)

SP-D (ng/ml)

7.41 (1.17 – 22.06)

5.41 (1.48 – 43.46)

6.25 (0.00 – 48.21)

Protein (μg/ml)

104.70 (52.60 – 382.40)

97.88 (46.60 – 193.40)

94.20 (38.44 – 258.80)

Phospholipids (μg/ml)

50.37 (19.45 – 102.50)

33.56 (20.75 – 429.40)

32.64 (14.84 – 70.00) **

  1. Comparisons were made by Friedman test followed by Dunn's post hoc test. Differences between the beginning and the end of the study are indicated by **, differences between the first and second BAL are indicated by †. Level of significance († P < 0.05, ** P < 0.01). Data are median (range) of 20 patients.