Figure 5

Quantification by densitometry of Pro-MMP-9 (105 kDa, A) and MMP-2 (64 kDa, B) gelatinase activity on zymograms of lung homogenates, performed 14 days after intranasal administration of bleomycin (BLM, 0.1 mg/mouse) or saline vehicle (Control) to p47^phox -/- KO mice (solid bars) and p47^phox +/+ WT mice (blank bars). Results are represented as the mean of relative intensity ± SEM. * : p < 0.05, ** : p < 0.01, compared with control mice exposed to saline solution alone. ##: p < 0.01 for p47^phox -/- [KO] mice compared with p47^phox +/+ WT mice. n = 3–5.