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Table 5 Disease-specific genes induced in the lower airways

From: dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls

Gene ID

FC rhinitis

p-value rhinitis

FC asthma

p-value asthma

Disease-specific

CFB

42.13

0.001

30.04

0.009

Significant p-value in patients with allergic rhinitis with or without asthma

MB

8.95

0.005

2.73

0.017

MAMDC2

3.2

0.009

1.58

0.06

XRCC6BP1

−2.01

0.005

−3.06

0.01

C4orf32

−3.06

0.027

−1.36

0.018

MPPE1

−3.31

0.016

−3.83

0.026

NEBL

−3.8

0.009

−3.35

0.012

GPC6

−5.11

0.001

−2.31

0.022

CYP1B1

−6.31

0.027

−2.39

0.027

CLN8

−6.39

0.001

−5

0.011

SHISA2

4.61

0.015

1.29

0.4

In patients with allergic rhinitis

S100A7A

4.07

0.017

1.38

0.4

NPFFR2

3.7

0.043

1.26

0.2

RDH10

3.37

0.016

1.1

0.6

BMP6

3.36

0.015

1.11

0.6

RNF141

−3.04

0.005

1.08

0.3

C12orf28

−3.08

0.037

−1.14

0.4

LOC148189

−3.23

0.023

−1.13

0.4

CRNN

−3.75

0.021

−1.07

0.9

PCK2

−4.16

0.024

−1.25

0.2

CTH

−5.08

0.046

−1.23

0.4

FLG

−5.17

0.004

−1.53

0.2

FANCD2

1.03

0.2

−3.03

0.014

In patients with allergic rhinitis with asthma

MYLK

−1.03

0.5

−3.1

0.005

SSR1

−1.16

0.4

−3.13

0.025

  1. FC = fold change; p-value = p-value adjusted for multiple testing.