Table 3 Most highly up-regulated genes in the lower airways
| Â | Healthy | Allergic rhinitis | Asthma | |||
|---|---|---|---|---|---|---|
Gene ID | FC | adj.P.Val | FC | adj.P.Val | FC | adj.P.Val |
CCL5 | 736.54 | 6.09E-08 | 322.77 | 1.61E-05 | 231.87 | 9.60E-03 |
CMPK2 | 395.26 | 2.56E-08 | 360.62 | 6.91E-06 | 164.40 | 8.69E-03 |
RSAD2 | 363.02 | 1.47E-07 | 304.55 | 6.91E-06 | 167.47 | 9.76E-03 |
CXCL11 | 315.72 | 1.08E-07 | 109.20 | 1.58E-04 | 156.95 | 8.45E-03 |
IFIT1 | 307.08 | 9.93E-08 | 281.31 | 2.49E-05 | 161.84 | 1.05E-02 |
IFI44L | 274.95 | 2.91E-08 | 211.91 | 1.08E-05 | 113.56 | 9.51E-03 |
CXCL10 | 263.55 | 2.97E-06 | 121.34 | 5.72E-04 | 88.92 | 1.09E-02 |
OASL | 241.59 | 6.78E-08 | 138.85 | 5.11E-05 | 160.96 | 8.11E-03 |
IFI44 | 236.92 | 4.06E-09 | 70.93 | 1.67E-05 | 104.82 | 9.45E-03 |
MX2 | 201.46 | 2.56E-08 | 163.72 | 1.64E-05 | 96.81 | 8.67E-03 |
MX1 | 140.44 | 1.43E-07 | 175.11 | 1.67E-05 | 67.81 | 9.45E-03 |
IFI6 | 165.88 | 5.52E-10 | 123.34 | 1.24E-05 | 77.06 | 9.76E-03 |
DEFB4A | 31.48 | 3.94E-04 | 137.90 | 2.06E-04 | 25.92 | 1.11E-02 |
LAMP3 | 131.90 | 2.15E-06 | 86.23 | 2.50E-04 | 50.68 | 1.39E-02 |
XAF1 | 110.43 | 6.45E-08 | 98.06 | 1.67E-05 | 61.68 | 7.99E-03 |
OAS1 | 109.84 | 1.13E-07 | 86.84 | 5.10E-05 | 47.06 | 1.05E-02 |
APOBEC3A | 101.03 | 3.84E-07 | 86.19 | 8.06E-04 | 74.29 | 7.44E-03 |
IFIT3 | 94.85 | 9.47E-08 | 88.51 | 5.73E-05 | 56.72 | 8.56E-03 |
CCL4 | 83.19 | 2.22E-04 | 20.90 | 2.27E-02 | 35.57 | 1.25E-02 |
CCL3 | 69.05 | 7.38E-04 | 17.00 | 4.78E-02 | 35.62 | 1.27E-02 |