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Table 4 Baseline characteristics of patients in the different groups of treatments (NO ICS)

From: Withdrawal of inhaled corticosteroids can be safe in COPD patients at low risk of exacerbation: a real-life study on the appropriateness of treatment in moderate COPD patients (OPTIMO)

 

NO ICS (n = 334)

 

Tiotropium (n = 89)

Formoterol/Salmeterol (n = 49)

Indacaterol (n = 98)

Tiotropium+Indacaterol (n = 67)

Other (n = 31)

Gender (%F)

28%

25%

28%

33%

36%

Age (Yrs)

72.0 (9.6)

71.5 (8.1)

71.4 (10.0)

73.4 (9.7)

71.7 (9.4)

BMI

27.4 (4.8)

27.2 (4.8)

27.5 (4.9)

28.3 (5.6)

28.0 (5.3)

Smoking history° (%Y)

79%

78%

84%

86%

83%

Years since diagnosis

5.4 (6.6)

8.7 (8.6)

7.3 (5.8)

6.4 (6.3)

7.2 (7.0)

VC (%pred)

96.1 (16.7)

90.5 (15.9)

91.2 (14.8)

88.6 (14.9)

89.4 (17.0)

FEV 1 (%pred)

75.2 (15.6)

72.0 (8.2)

72.8 (10.2)

67.5 (6.9)

68.1 (12.1)

FEV 1 /VC

0.61 (0.10)

0.60 (0.08)

0.60 (0.08)

0.59 (0.08)

0.59 (0.04)

CAT

13.8 (7.2)

13.3 (5.8)

14.7 (8.0)

21.9 (9.2)

15.0 (8.6)

Exacerbations (0/1)

35/54

13/36

33/65

31/36

10/21

Comorbidities: 0

31 (35%)

20 (41%)

32 (33%)

17 (26%)

6 (19%)

Comorbidities: 1

23 (26%)

16 (33%)

27 (27%)

24 (36%)

10 (31%)

Comorbidities: ≥2

35 (39%)

13 (26%)

39 (40%)

26 (38%)

15 (50%)

  1. Data are presented as N, unless otherwise stated. Values are expressed as mean (SD).
  2. BMI: Body Mass Index; VC: Vital Capacity; FEV1: Forced Expiratory Volume in 1 second; CAT: COPD Assessment Test.
  3. °Y = includes current smokers and ex-smokers.