Table 1 Patient’s characteristics
Parameter | No pathogen detected (n = 101) | Influenza (n = 50) | Legionella (n = 49) | Streptococcus pneumonia (n = 100) | ANOVA resp. Fishers exact test | |||||
|---|---|---|---|---|---|---|---|---|---|---|
n | n | n | n | Test statistic | p value | |||||
Age (mean, SD) | 59.43 | 15.9 | 60.13 | 17.8 | 62.65 | 16.7 | 57.41 | 17.0 | F3,296 = 1.12 | 0.3403 |
Sex (male % n)* | 61.4% | 62 | 52.0% | 26 | 71.4% | 35 | 49.0% | 49 | 0.0437 | |
Active smoker | 40.6% | 41 | 38.0% | 19 | 36.7% | 18 | 43.0% | 43 | 0.8855 | |
Heart insufficiency | 11.9% | 12 | 12.0% | 6 | 20.4% | 10 | 11.1% | 11 | 0.4435 | |
Cerebrovascular co-morbidity | 5.1% | 5 | 10.0% | 5 | 2.0% | 1 | 7.0% | 7 | 0.3649 | |
Diabetes mellitus | 13.9% | 14 | 10.0% | 5 | 22.4% | 11 | 13.0% | 13 | 0.3454 | |
Respiratory co-morbidity | 33.0% | 33 | 30.0% | 15 | 38.8% | 19 | 32.0% | 32 | 0.8059 | |
Hepatic co-morbidity* | 0.0% | 0 | 2.0% | 1 | 6.1% | 3 | 7.0% | 7 | 0.0167 | |
Renal co-morbidity | 5.0% | 5 | 6.0% | 3 | 12.2% | 6 | 6.0% | 6 | 0.4034 | |
Vaccination with the 23 PPV | 14.3% | 14 | 10.0% | 5 | 14.3% | 7 | 6.1% | 6 | 0.1158 | |
Vaccination with the TIV | 38.4% | 38 | 32.0% | 16 | 37.5% | 18 | 23.5% | 23 | ||
From nursing home | 3.0% | 3 | 2.0% | 1 | 0.0% | 0 | 4.0% | 4 | ||
CURB-index | 0.2829 | |||||||||
0 | 56.0% | 42 | 50.0% | 21 | 55.6% | 20 | 38.7% | 29 | ||
1 | 32.0% | 24 | 38.1% | 16 | 33.3% | 12 | 52.0% | 39 | ||
2 | 10.7% | 8 | 11.9% | 5 | 8.3% | 3 | 9.3% | 7 | ||
3 | 1.3% | 1 | 0.0% | 0 | 2.8% | 1 | 0.0% | 0 | ||
Hospitalization | 58.2% | 57 | 65.3% | 32 | 75.5% | 37 | 71.1% | 69 | 0.1259 | |
180 day mortality | 7.1% | 7 | 4.1% | 2 | 6.4% | 3 | 1.0% | 1 | 0.1154 | |
30 day mortality | 1.0% | 1 | 2.1% | 1 | 2.1% | 1 | 0.0% | 0 | ||
Deficient/insufficient/sufficient | 74.3/16.8/8.9% | 75/17/9 | 92.0/2.0/6.0% | 46/1/3 | 77.6/22.4/0% | 38/11/0 | 82.3/12.7/5.0% | 87/9/3 | ||
D3 25 OH [ng/ml] (mean ± SD)** | 16.2 ± 9.0 | 11.3 ± 9.7 | 14.1 ± 7.1 | 12.9 ± 7.4 | F3,295 = 6.66 | 0.0002 | ||||
D3 1,25 OH2 [pg/ml] (mean ± SD)*** | 51.5 ± 24.6 | 54.5 ± 37.6 | 52.4 ± 38.4 | 42.4 ± 23.0 | F3,295 = 2.43 | 0.0651 | ||||
CRP [mg/l] (mean ± SD)* | 105.2 ± 108.7 | 65.1 ± 70.1 | 136.2 ± 142.7 | 192.7 ± 150.3 | F3,274 = 10.69 | <0.0001 | ||||