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Figure 1 | Respiratory Research

Figure 1

From: Bifidobacterium breve and Lactobacillus rhamnosus treatment is as effective as budesonide at reducing inflammation in a murine model for chronic asthma

Figure 1

Time schedule of the chronic asthma mouse model. Male BALB/c mice were sensitised intraperitoneally to OVA-ImjectAlum on days 0 and 12 and mice were challenged from day 17 until day 23 daily with aerosolised OVA or saline. From day 22 until day 55, mice were treated 3 times a week with either PBS or budesonide by oropharyngeal aspiration or beneficial bacteria (B. breve or L. rhamnosus) by oral gavage. 1 h after treatment, from day 24 until day 55, mice were challenged 3 times/week with aerosolised OVA or saline. Mice were sacrificed on day 56 after pulmonary function measurement.

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