Characteristics | Control (n = 9) | COPD > 70 cm2(n = 11) | COPD < 70 cm2(n = 6) |
---|---|---|---|
Age (years) | 63 ± 2.3 | 64 ± 2.3 | 70 ± 2.4 |
BMI (kg/m 2 ) | 29.1 ± 2.4 | 28.1 ± 2.0 | 21.7 ± 2.6b |
FEV 1 , L | 3.3 ± 0.2 | 1.0 ± 0.2a | 0.8 ± 0.1a |
FEV 1, % predicted | 106.3 ± 4.1 | 36.0 ± 4.9a | 26.0 ± 3.8a |
FEV 1 /FVC, % | 76.0 ± 1.6 | 36.1 ± 1.8a | 29.0 ± 2.6b |
TLC, % predicted | 98.6 ± 6.5 | 121.6 ± 6.6a | 125.7 ± 4.8a |
RV, % predicted | 90.1 ± 15.3 | 173.2 ± 22.8a | 195.5 ± 22.9a |
DL CO , % predicted | 96.9 ± 3.2 | 57.4 ± 6.7a | 40.0 ± 2.8b |
MTCSA (cm 2 ) | 120.3 ± 3.4 | 86.3 ± 4.2a | 60.8 ± 3.6b |
Type I fiber | |||
Distribution, % | 51.5 ± 5.7 | 34.7 ± 9.3a | 34.9 ± 3.5a |
CSA, (μm 2 ) | 5170 ± 471 | 4711 ± 340 | 4883 ± 607 |
Type II fiber | |||
Distribution, % | 44.1 ± 5.7 | 65.4 ± 9.3a | 65.2 ± 3.5a |
CSA, (μm 2 ) | 4216 ± 358 | 4359 ± 540 | 4096 ± 480 |