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Figure 2 | Respiratory Research

Figure 2

From: Rosiglitazone is a superior bronchodilator compared to chloroquine and β-adrenoceptor agonists in mouse lung slices

Figure 2

Rosiglitazone and chloroquine, but not isoproterenol, albuterol or saccharin, elicit full relaxation of mouse small airways in lung slices. Airways were A) pre-contracted with 100 nM methacholine (MCh) to achieve ~25% reduction in lumen area over 5 min prior to B) cumulative additions of albuterol (ALB, n = 9), isoproterenol (ISO, n = 7), rosiglitazone (RGZ, n = 4), chloroquine (CQ, n = 6) or saccharin (SACC, n = 4) at 5 min intervals. Responses (mean ± S.E.M) represent A) the reduction in lumen area to MCh and B) the% relaxation of this pre-contraction averaged over the last minute of each perfusion.

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Respiratory Research

ISSN: 1465-993X

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