Figure 6
The effect of AR, HB-EGF, and TGF-α neutralising antibodies on DEP induced IL-8 release. The relative release of IL-8 from PBECs after exposure to DEP 50 μg/ml for 24 h in the absence or presence of TGFα, HB-EGF or AR neutralising antibodies was determined. Data show mean ± SD (n = 3). SFM = serum free medium, D50 = DEP 50 μg/ml, DTGFab = D50 + antibody to TGF-α, DARab = D50 + antibody to AR, DHBEGFab = D50 + antibody to HB-EGF, DTGF = D50 + antibody to all three ligands (TGF-α, AR, HB-EGF).