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Table 2 Mitochondrial shape variation and density of the matrix

From: Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

 

Shape

Status of matrix

 

Rod

Branching

Fragmented

Clear

Dense (Lipoid)

Control

28 (93.3%)

0 (0.0%)

2 (6.7%)

30 (100.0%)

0 (0.0%)

1% CSE

25 (80.6%)

6 (19.4%)

0 (0.0%)

31 (100.0%)

0 (0.0%)

2.5% CSE

31 (96.9%)

0 (0.0%)

1 (3.1%)

28 (87.5%)

4 (12.5%)

10% CSE

24 (70.6%)

2 (5.9%)

8 (23.5%)

23 (67.6%)

11 (32.4%)

12.5% CSE

24 (69.6%)

3 (8.6%)

8 (22.9%)

29 (82.9%)

6 (17.1%)

-10% CSE

19 (63.3%)

9 (30.0%)

1 (3.1%)

22 (73.3%)

8 (26.7%)

 

***

***

  1. ***Estimated by chi-square test (p < 0.001).
  2. BEAS-2B cells were exposed to various concentrations of cigarette smoke extract (CSE) for 6 months and subjected to EM analysis. BEAS-2B cells are exposed to: 0% CSE (control), 1% CSE, 2.5% CSE, 10% CSE, 12.5% CSE and -10% CSE (depletion). In total of 30–35 mitochondria were analyzed per experimental condition. Significance was determined by chi-square test.
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Respiratory Research

ISSN: 1465-993X

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