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Table 2 Mitochondrial shape variation and density of the matrix

From: Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

  Shape Status of matrix
  Rod Branching Fragmented Clear Dense (Lipoid)
Control 28 (93.3%) 0 (0.0%) 2 (6.7%) 30 (100.0%) 0 (0.0%)
1% CSE 25 (80.6%) 6 (19.4%) 0 (0.0%) 31 (100.0%) 0 (0.0%)
2.5% CSE 31 (96.9%) 0 (0.0%) 1 (3.1%) 28 (87.5%) 4 (12.5%)
10% CSE 24 (70.6%) 2 (5.9%) 8 (23.5%) 23 (67.6%) 11 (32.4%)
12.5% CSE 24 (69.6%) 3 (8.6%) 8 (22.9%) 29 (82.9%) 6 (17.1%)
-10% CSE 19 (63.3%) 9 (30.0%) 1 (3.1%) 22 (73.3%) 8 (26.7%)
  *** ***
  1. ***Estimated by chi-square test (p < 0.001).
  2. BEAS-2B cells were exposed to various concentrations of cigarette smoke extract (CSE) for 6 months and subjected to EM analysis. BEAS-2B cells are exposed to: 0% CSE (control), 1% CSE, 2.5% CSE, 10% CSE, 12.5% CSE and -10% CSE (depletion). In total of 30–35 mitochondria were analyzed per experimental condition. Significance was determined by chi-square test.