Figure 6

Respiratory DC-subset specific expression of MHC-class II, CD86 and CD274 at different timepoints during acute Klebsiella pneumonia infection. Surface MHC-class II, CD86 and CD274 on total respiratory DC (DC) and DC subsets (pDC, CD103⁺ DC, MoDC, CD11b⁺ DC) were analyzed by flow cytometry during acute and post-acute Klebsiella pneumonia (Kp) infection (48 h and d5 p.i.) and compared to mock-infected control (ctr) animals (A, B). MFI is median fluorescence intensity; mean ± SEM; n ≥ 3; *p < 0.05; **p < 0.01; ***p < 0.001 versus mock-infected controls (A-B).